SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03459

Signal sequence   MDYPTLLLALLHVYRALC

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q15762,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03459.cif

Structure  SPKB03459.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2105.58424

Aliphatic index  157.2222222

Isoelectric point  7.352689023

Charge (pH=7)   0.025661019

Topological polar surface area  737.8

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -1.21743

Hydropathy 



Literature Information


Title  DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes.

DOI  10.1016/s1074-7613(00)70060-4,

Publication Year  1996

PubMed ID  8673704,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.