SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03458

Signal sequence   MALFVRLLALALALALGPAATLA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q15582,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03458.cif

Structure  SPKB03458.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2280.88384

Aliphatic index  183.0434783

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  776.86

Aromaticity  0.043478261

Average rotatable bonds  3.086956522

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -1.97463

Hydropathy 



Literature Information


Title  beta ig-h3: a transforming growth factor-beta-responsive gene encoding a secreted protein that inhibits cell attachment in vitro and suppresses the growth of CHO cells in nude mice.

DOI  10.1089/dna.1994.13.571,

Publication Year  1994

PubMed ID  8024701,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.