General Information
SPKB ID SPKB03458
Signal sequence MALFVRLLALALALALGPAATLA
Length 23
Organism Homo sapiens (Human)
UniProt ID Q15582,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03458.cif
Physicochemical Information
Molecular weight 2280.88384
Aliphatic index 183.0434783
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 776.86
Aromaticity 0.043478261
Average rotatable bonds 3.086956522
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 27
X logP energy -1.97463
Hydropathy
Literature Information
Title beta ig-h3: a transforming growth factor-beta-responsive gene encoding a secreted protein that inhibits cell attachment in vitro and suppresses the growth of CHO cells in nude mice.
Publication Year 1994
PubMed ID 8024701,
Patent ID NA,