General Information
SPKB ID SPKB03457
Signal sequence MLLLARCLLLVLVSSLLVCSGLA
Length 23
Organism Homo sapiens (Human)
UniProt ID Q15465,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7E2I,
Predicted Structure ID SPKB03457.cif
Physicochemical Information
Molecular weight 2401.10884
Aliphatic index 216.0869565
Isoelectric point 8.231408964
Charge (pH=7) 0.874031556
Topological polar surface area 826.11
Aromaticity 0
Average rotatable bonds 3.47826087
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 31
X logP energy -2.98303
Hydropathy 
Literature Information
Title Identification of a palmitic acid-modified form of human Sonic hedgehog.
Publication Year 1998
PubMed ID 9593755,
Patent ID NA,
