SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03455

Signal sequence   MALLVLGLVSCTFFLAVNG

Length  19

Organism  Homo sapiens (Human)

UniProt ID  Q15084,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03455.cif

Structure  SPKB03455.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1968.44314

Aliphatic index  158.9473684

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  670.67

Aromaticity  0.105263158

Average rotatable bonds  3.263157895

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -2.9574

Hydropathy 



Literature Information


Title  A role for the thiol isomerase protein ERP5 in platelet function.

DOI  10.1182/blood-2004-02-0608,

Publication Year  2005

PubMed ID  15466936,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.