General Information
SPKB ID SPKB03453
Signal sequence MKPPRPVRTCSKVLVLLSLLAIHQTTTA
Length 28
Organism Homo sapiens (Human)
UniProt ID Q14624,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9C4F,
Predicted Structure ID SPKB03453.cif
Physicochemical Information
Molecular weight 3074.78034
Aliphatic index 121.7857143
Isoelectric point 11.65160089
Charge (pH=7) 4.026321984
Topological polar surface area 1191.64
Aromaticity 0
Average rotatable bonds 3.5
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 43
X logP energy -10.50256
Hydropathy
Literature Information
Title Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma.
DOI 10.1093/jb/117.2.400,
Publication Year 1995
PubMed ID 7541790,
Patent ID NA,