General Information
SPKB ID SPKB03451
Signal sequence MRPQILLLLALLTLGLAAQ
Length 19
Organism Homo sapiens (Human)
UniProt ID Q14392,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03451.cif
Physicochemical Information
Molecular weight 2048.60144
Aliphatic index 200.5263158
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 746.64
Aromaticity 0
Average rotatable bonds 3.578947368
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -2.33493
Hydropathy 
Literature Information
Title Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32).
Publication Year 2011
PubMed ID 21615933,
Patent ID NA,
