SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03448

Signal sequence   MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQ

Length  35

Organism  Homo sapiens (Human)

UniProt ID  Q14002,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03448.cif

Structure  SPKB03448.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3836.49934

Aliphatic index  94.85714286

Isoelectric point  8.222829177

Charge (pH=7)   0.873181142

Topological polar surface area  1425.01

Aromaticity  0.114285714

Average rotatable bonds  3.228571429

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  51

X logP energy  -12.26493

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.