SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03447

Signal sequence   MAGARSRDPWGASGICYLFGSLLVELLFSRAVA

Length  33

Organism  Homo sapiens (Human)

UniProt ID  Q13683,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03447.cif

Structure  SPKB03447.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3515.10834

Aliphatic index  103.6363636

Isoelectric point  8.527087512

Charge (pH=7)   0.937370842

Topological polar surface area  1362.97

Aromaticity  0.121212121

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  46

X logP energy  -11.42909

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.