SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03445

Signal sequence   MNCRELPLTLWVLISVST

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q13478,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03445.cif

Structure  SPKB03445.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2075.51214

Aliphatic index  140.5555556

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  788.23

Aromaticity  0.055555556

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  28

X logP energy  -5.15483

Hydropathy 



Literature Information


Title  Purification and characterization of the human interleukin-18 receptor.

DOI  10.1074/jbc.272.41.25737,

Publication Year  1997

PubMed ID  9325300,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.