General Information
SPKB ID SPKB03444
Signal sequence MMAAGAALALALWLLMPPVEVGG
Length 23
Organism Homo sapiens (Human)
UniProt ID Q13445,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03444.cif
Physicochemical Information
Molecular weight 2282.84584
Aliphatic index 136.0869565
Isoelectric point 3.849983241
Charge (pH=7) -1.000240578
Topological polar surface area 739.03
Aromaticity 0.043478261
Average rotatable bonds 3
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 28
X logP energy -1.5195
Hydropathy
Literature Information
Title Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini.
Publication Year 2009
PubMed ID 19892738,
Patent ID NA,