SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03442

Signal sequence   MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRT

Length  36

Organism  Homo sapiens (Human)

UniProt ID  Q13421,

Motif  1..36



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03442.cif

Structure  SPKB03442.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3772.52484

Aliphatic index  113.8888889

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1370.95

Aromaticity  0.083333333

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  49

X logP energy  -11.15676

Hydropathy 



Literature Information


Title  Molecular cloning and expression of megakaryocyte potentiating factor cDNA.

DOI  10.1074/jbc.270.37.21984,

Publication Year  1995

PubMed ID  7665620,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.