SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03441

Signal sequence   MVRSVAWAGFMVLLMIPWGSA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q13231,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5HBF,

Predicted Structure ID  SPKB03441.cif

Structure  SPKB03441.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2322.87284

Aliphatic index  111.4285714

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  770.47

Aromaticity  0.142857143

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -1.77283

Hydropathy 



Literature Information


Title  Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.

DOI  10.1074/jbc.270.5.2198,

Publication Year  1995

PubMed ID  7836450,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.