General Information
SPKB ID SPKB03440
Signal sequence MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQG
Length 37
Organism Homo sapiens (Human)
UniProt ID Q13162,
Motif 1..37
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8EKW,
Predicted Structure ID SPKB03440.cif
Physicochemical Information
Molecular weight 3985.83604
Aliphatic index 147.8378378
Isoelectric point 10.31217267
Charge (pH=7) 1.182014154
Topological polar surface area 1476.97
Aromaticity 0.027027027
Average rotatable bonds 3.378378378
Number of hydrogen bond donors 50
Number of hydrogen bond acceptors 49
X logP energy -7.83739
Hydropathy 
Literature Information
Title Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini.
Publication Year 2009
PubMed ID 19892738,
Patent ID NA,
