General Information
SPKB ID SPKB03436
Signal sequence MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMVHG
Length 46
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
UniProt ID Q12396,
Motif 1..46
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03436.cif
Physicochemical Information
Molecular weight 5187.29014
Aliphatic index 84.7826087
Isoelectric point 11.11842132
Charge (pH=7) 7.024294746
Topological polar surface area 2005.53
Aromaticity 0.086956522
Average rotatable bonds 3.869565217
Number of hydrogen bond donors 73
Number of hydrogen bond acceptors 73
X logP energy -16.77263
Hydropathy
Literature Information
Title Emp47p and its close homolog Emp46p have a tyrosine-containing endoplasmic reticulum exit signal and function in glycoprotein secretion in Saccharomyces cerevisiae.
Publication Year 2002
PubMed ID 12134087,
Patent ID NA,