SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03435

Signal sequence   MQFSTVASIAAVAAVASA

Length  18

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  Q12127,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03435.cif

Structure  SPKB03435.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1694.96364

Aliphatic index  108.8888889

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  682.03

Aromaticity  0.055555556

Average rotatable bonds  2.888888889

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -8.5877

Hydropathy 



Literature Information


Title  Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae.

DOI  10.1128/JB.181.10.3076-3086.1999,

Publication Year  1999

PubMed ID  10322008,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.