SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03434

Signal sequence   MAPPTRRLLNAALLLLLLLMATSHQPSGTVVA

Length  32

Organism  Rattus norvegicus (Rat)

UniProt ID  Q10746,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03434.cif

Structure  SPKB03434.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3370.11854

Aliphatic index  143.4375

Isoelectric point  12.50011018

Charge (pH=7)   2.088886768

Topological polar surface area  1278.86

Aromaticity  0

Average rotatable bonds  3.3125

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  45

X logP energy  -10.33006

Hydropathy 



Literature Information


Title  Production of an interleukin-8-like chemokine by cytokine-stimulated rat NRK-49F fibroblasts and its suppression by anti-inflammatory steroids.

DOI  10.1016/0006-2952(93)90041-t,

Publication Year  1993

PubMed ID  8471066,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.