SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03432

Signal sequence   MKRKICKALICAALATSLWAGASTKVYA

Length  28

Organism  Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)

UniProt ID  Q0TV31,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03432.cif

Structure  SPKB03432.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2969.65824

Aliphatic index  105

Isoelectric point  10.48912472

Charge (pH=7)   4.872001007

Topological polar surface area  1131.94

Aromaticity  0.071428571

Average rotatable bonds  3.535714286

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -9.04443

Hydropathy 



Literature Information


Title  Molecular cloning and nucleotide sequence of the alpha-toxin (phospholipase C) of Clostridium perfringens.

DOI  10.1128/iai.57.2.367-376.1989,

Publication Year  1989

PubMed ID  2536355,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.