SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03431

Signal sequence   MFVLNEFTRRGFLGTAAAVGGTTVVTTALGGAPAAQAAVPEAA

Length  43

Organism  Streptomyces galilaeus

UniProt ID  Q0PCD7,

Motif  1..43



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03431.cif

Structure  SPKB03431.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4163.76154

Aliphatic index  86.51162791

Isoelectric point  6.533466308

Charge (pH=7)   0.001527922

Topological polar surface area  1673.9

Aromaticity  0.069767442

Average rotatable bonds  2.976744186

Number of hydrogen bond donors  58

Number of hydrogen bond acceptors  57

X logP energy  -19.63906

Hydropathy 



Literature Information


Title  Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.

DOI  10.1073/pnas.0700579104,

Publication Year  2007

PubMed ID  17395717,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.