SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03430

Signal sequence   MNTKLTVLCFLGIVTIVSC

Length  19

Organism  Hoffmannihadrurus gertschi (Scorpion) (Hadrurus gertschi)

UniProt ID  Q0GY40,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03430.cif

Structure  SPKB03430.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2055.58014

Aliphatic index  148.4210526

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  737.15

Aromaticity  0.052631579

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.0509

Hydropathy 



Literature Information


Title  Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.

DOI  10.1016/j.peptides.2006.06.012,

Publication Year  2007

PubMed ID  17141373,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.