SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03423

Signal sequence   MAKVFSFILVTTALTMGREISA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q08830,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03423.cif

Structure  SPKB03423.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2386.89354

Aliphatic index  110.9090909

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  900.79

Aromaticity  0.090909091

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -6.85773

Hydropathy 



Literature Information


Title  Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activity.

DOI  10.1016/s0167-4781(01)00249-4,

Publication Year  2001

PubMed ID  11470158,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.