SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03417

Signal sequence   MKKSGVLFLLGIILLVLIGVQG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q07325,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03417.cif

Structure  SPKB03417.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2311.98154

Aliphatic index  199.0909091

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  789.78

Aromaticity  0.045454545

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -1.0008

Hydropathy 



Literature Information


Title  Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).

DOI  10.1046/j.1523-1747.1999.00581.x,

Publication Year  1999

PubMed ID  10233762,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.