SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03416

Signal sequence   MSFTLHSVFFTLKVSSFLGSLVGLCLG

Length  27

Organism  Rattus norvegicus (Rat)

UniProt ID  Q07310,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03416.cif

Structure  SPKB03416.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2891.47934

Aliphatic index  118.8888889

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  1016.23

Aromaticity  0.148148148

Average rotatable bonds  3.444444444

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  39

X logP energy  -7.3865

Hydropathy 



Literature Information


Title  Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.

DOI  10.1074/jbc.273.52.34716,

Publication Year  1998

PubMed ID  9856994,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.