SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03410

Signal sequence   MDPTAPGSSVSSLPLLLVLALGLAILHCVVA

Length  31

Organism  Mus musculus (Mouse)

UniProt ID  Q05928,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03410.cif

Structure  SPKB03410.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3058.72834

Aliphatic index  163.5483871

Isoelectric point  5.289877379

Charge (pH=7)   -0.972634841

Topological polar surface area  1077.08

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  41

X logP energy  -7.6844

Hydropathy 



Literature Information


Title  Betacellulin: a mitogen from pancreatic beta cell tumors.

DOI  10.1126/science.8456283,

Publication Year  1993

PubMed ID  8456283,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.