SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03409

Signal sequence   MNPGAARTPALRILALGALLWPAARP

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  Q05927,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03409.cif

Structure  SPKB03409.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2698.27104

Aliphatic index  116.9230769

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  1020.47

Aromaticity  0.038461538

Average rotatable bonds  3.038461538

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  33

X logP energy  -7.25509

Hydropathy 



Literature Information


Title  Purification and cDNA cloning of bovine liver 5'-nucleotidase, a GPI-anchored protein, and its expression in COS cells.

DOI  10.1093/oxfordjournals.jbchem.a124090,

Publication Year  1993

PubMed ID  8340354,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.