SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03408

Signal sequence   MEKPELWGVLALLLLCSYTCG

Length  21

Organism  Mus musculus (Mouse)

UniProt ID  Q05895,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03408.cif

Structure  SPKB03408.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2339.85134

Aliphatic index  130

Isoelectric point  4.258067521

Charge (pH=7)   -1.123560335

Topological polar surface area  813.63

Aromaticity  0.095238095

Average rotatable bonds  3.523809524

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.6675

Hydropathy 



Literature Information


Title  Expression and initial characterization of recombinant mouse thrombospondin 1 and thrombospondin 3.

DOI  10.1016/0014-5793(96)00460-7,

Publication Year  1996

PubMed ID  8654563,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.