SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03407

Signal sequence   MKKQILYLIVLQQLFLCSAYA

Length  21

Organism  Pedobacter heparinus (Flavobacterium heparinum)

UniProt ID  Q05819,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03407.cif

Structure  SPKB03407.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2487.09974

Aliphatic index  153.3333333

Isoelectric point  9.274958252

Charge (pH=7)   1.933718687

Topological polar surface area  887.32

Aromaticity  0.142857143

Average rotatable bonds  4

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -2.0182

Hydropathy 



Literature Information


Title  Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum.

DOI  10.1042/bj3150589,

Publication Year  1996

PubMed ID  8615834,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.