SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03405

Signal sequence   MLLTSLLQVFACCLVLPAQVTA

Length  22

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  Q05359,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03405.cif

Structure  SPKB03405.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2334.91914

Aliphatic index  159.5454545

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  812.5

Aromaticity  0.045454545

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -4.4701

Hydropathy 



Literature Information


Title  Proteins in the early golgi compartment of Saccharomyces cerevisiae immunoisolated by Sed5p.

DOI  10.1016/s0014-5793(00)01268-0,

Publication Year  2000

PubMed ID  10713261,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.