General Information
SPKB ID SPKB03401
Signal sequence MGHPPLLPLLLLLHTCVPASWG
Length 22
Organism Homo sapiens (Human)
UniProt ID Q03405,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03401.cif
Physicochemical Information
Molecular weight 2365.92314
Aliphatic index 141.8181818
Isoelectric point 7.523974965
Charge (pH=7) 0.117827765
Topological polar surface area 752.87
Aromaticity 0.045454545
Average rotatable bonds 3
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 29
X logP energy -1.4231
Hydropathy
Literature Information
Title Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.
DOI 10.1002/j.1460-2075.1990.tb08132.x,
Publication Year 1990
PubMed ID 1689240,
Patent ID NA,