SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03401

Signal sequence   MGHPPLLPLLLLLHTCVPASWG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q03405,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03401.cif

Structure  SPKB03401.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2365.92314

Aliphatic index  141.8181818

Isoelectric point  7.523974965

Charge (pH=7)   0.117827765

Topological polar surface area  752.87

Aromaticity  0.045454545

Average rotatable bonds  3

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -1.4231

Hydropathy 



Literature Information


Title  Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

DOI  10.1002/j.1460-2075.1990.tb08132.x,

Publication Year  1990

PubMed ID  1689240,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.