SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03398

Signal sequence   MNKAYSIIWSHSRQAWIVASELARGHGFVLAKNTLLVLAVVSTIGNAFA

Length  49

Organism  Escherichia coli

UniProt ID  Q03155,

Motif  1..49



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03398.cif

Structure  SPKB03398.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5313.21134

Aliphatic index  117.5510204

Isoelectric point  10.88581289

Charge (pH=7)   3.180130499

Topological polar surface area  2096.4

Aromaticity  0.102040816

Average rotatable bonds  3.510204082

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  70

X logP energy  -17.75246

Hydropathy 



Literature Information


Title  AIDA-I, the adhesin involved in diffuse adherence of the diarrhoeagenic Escherichia coli strain 2787 (O126:H27), is synthesized via a precursor molecule.

DOI  10.1111/j.1365-2958.1992.tb00875.x,

Publication Year  1992

PubMed ID  1625582,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.