SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03396

Signal sequence   MRPLLLLALLGWLLLAEA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q02809,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03396.cif

Structure  SPKB03396.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2006.56364

Aliphatic index  211.6666667

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  664.22

Aromaticity  0.055555556

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  1.85727

Hydropathy 



Literature Information


Title  Cloning of human lysyl hydroxylase: complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3----p36.2.

DOI  10.1016/0888-7543(92)90202-4,

Publication Year  1992

PubMed ID  1577494,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.