General Information
SPKB ID SPKB03395
Signal sequence MQFFKTLAALVSCISFVLA
Length 19
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
UniProt ID Q02795,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6C26,
Predicted Structure ID SPKB03395.cif
Physicochemical Information
Molecular weight 2089.58194
Aliphatic index 128.4210526
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 716.92
Aromaticity 0.157894737
Average rotatable bonds 3.526315789
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -3.1483
Hydropathy
Literature Information
Title Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity.
DOI 10.1021/bi00013a005,
Publication Year 1995
PubMed ID 7703229,
Patent ID NA,