SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03395

Signal sequence   MQFFKTLAALVSCISFVLA

Length  19

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  Q02795,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6C26,

Predicted Structure ID  SPKB03395.cif

Structure  SPKB03395.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2089.58194

Aliphatic index  128.4210526

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  716.92

Aromaticity  0.157894737

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -3.1483

Hydropathy 



Literature Information


Title  Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity.

DOI  10.1021/bi00013a005,

Publication Year  1995

PubMed ID  7703229,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.