General Information
SPKB ID SPKB03393
Signal sequence MNAFLLSALCLLGAWAALAGG
Length 21
Organism Homo sapiens (Human)
UniProt ID Q02747,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03393.cif
Physicochemical Information
Molecular weight 2063.50334
Aliphatic index 140
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 724.43
Aromaticity 0.095238095
Average rotatable bonds 3.047619048
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -4.0982
Hydropathy 
Literature Information
Title The circulating bioactive form of human guanylin is a high molecular weight peptide (10.3 kDa).
DOI 10.1016/0014-5793(93)80022-m,
Publication Year 1993
PubMed ID 8095028,
Patent ID NA,
