SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03390

Signal sequence   MGTATRRKPHLLLVAAVALVSSSAWSSALG

Length  30

Organism  Homo sapiens (Human)

UniProt ID  Q02246,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03390.cif

Structure  SPKB03390.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3051.60054

Aliphatic index  114

Isoelectric point  12.51647895

Charge (pH=7)   3.088591734

Topological polar surface area  1234.33

Aromaticity  0.033333333

Average rotatable bonds  3.233333333

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  43

X logP energy  -13.63406

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.