SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03388

Signal sequence   MRTADREARPGLPSLLLLLLAGAGLSAA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  Q02083,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03388.cif

Structure  SPKB03388.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2834.37304

Aliphatic index  132.8571429

Isoelectric point  10.30863985

Charge (pH=7)   1.000195972

Topological polar surface area  1152.43

Aromaticity  0

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  38

X logP energy  -10.86949

Hydropathy 



Literature Information


Title  Mass spectrometric characterization of human N-acylethanolamine-hydrolyzing acid amidase.

DOI  10.1021/pr200735a,

Publication Year  2012

PubMed ID  22040171,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.