SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03382

Signal sequence   MGTLLALVVGAVLVSSAW

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  Q00954,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03382.cif

Structure  SPKB03382.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1787.19074

Aliphatic index  167.7777778

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  634.5

Aromaticity  0.055555556

Average rotatable bonds  3.055555556

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  23

X logP energy  -3.3867

Hydropathy 



Literature Information


Title  Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel.

DOI  10.1126/science.1375395,

Publication Year  1992

PubMed ID  1375395,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.