SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03379

Signal sequence   MTPRSLVRIVGVVVATTLALVSAPAGGRAAHA

Length  32

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  P9WP43,

Motif  1..32



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03379.cif

Structure  SPKB03379.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3142.75704

Aliphatic index  125

Isoelectric point  12.80107132

Charge (pH=7)   3.088883456

Topological polar surface area  1263.37

Aromaticity  0

Average rotatable bonds  3.03125

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  43

X logP energy  -13.77089

Hydropathy 



Literature Information


Title  Two-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins.

DOI  10.1128/IAI.66.8.3492-3500.1998,

Publication Year  1998

PubMed ID  9673225,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.