General Information
SPKB ID SPKB03378
Signal sequence MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANA
Length 39
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
UniProt ID P9WIR7,
Motif 1..39
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Cell surface
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5ZX9,
Predicted Structure ID SPKB03378.cif
Physicochemical Information
Molecular weight 3958.65624
Aliphatic index 107.9487179
Isoelectric point 12.22263642
Charge (pH=7) 3.089034907
Topological polar surface area 1659.66
Aromaticity 0
Average rotatable bonds 3.256410256
Number of hydrogen bond donors 58
Number of hydrogen bond acceptors 56
X logP energy -19.45329
Hydropathy 
Literature Information
Title Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses.
DOI 10.1128/IAI.67.11.5567-5572.1999,
Publication Year 1999
PubMed ID 10531201,
Patent ID NA,
