SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03377

Signal sequence   MLTRPREIYLATAVSIGILLSLIAPLGPPLARA

Length  33

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  P9WIB9,

Motif  1..33



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03377.cif

Structure  SPKB03377.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3488.27904

Aliphatic index  153.9393939

Isoelectric point  11.05363841

Charge (pH=7)   1.998899074

Topological polar surface area  1283.51

Aromaticity  0.03030303

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  44

X logP energy  -7.43569

Hydropathy 



Literature Information


Title  Characterization of the secreted chorismate mutase from the pathogen Mycobacterium tuberculosis.

DOI  10.1111/j.1742-4658.2004.04478.x,

Publication Year  2005

PubMed ID  15654876,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.