General Information
SPKB ID SPKB03375
Signal sequence MIILIYLFLLLWEDTQG
Length 17
Organism Homo sapiens (Human)
UniProt ID P98066,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03375.cif
Physicochemical Information
Molecular weight 2081.54064
Aliphatic index 183.5294118
Isoelectric point 3.550073361
Charge (pH=7) -2.000644508
Topological polar surface area 702.86
Aromaticity 0.176470588
Average rotatable bonds 3.941176471
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 24
X logP energy 1.8092
Hydropathy
Literature Information
Title TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor.
DOI 10.1021/bi00189a049,
Publication Year 1994
PubMed ID 7516184,
Patent ID NA,