SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03375

Signal sequence   MIILIYLFLLLWEDTQG

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P98066,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03375.cif

Structure  SPKB03375.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2081.54064

Aliphatic index  183.5294118

Isoelectric point  3.550073361

Charge (pH=7)   -2.000644508

Topological polar surface area  702.86

Aromaticity  0.176470588

Average rotatable bonds  3.941176471

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  1.8092

Hydropathy 



Literature Information


Title  TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor.

DOI  10.1021/bi00189a049,

Publication Year  1994

PubMed ID  7516184,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.