SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03374

Signal sequence   MACKHLPFLALAGVLLAYLCSQSEAA

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  P97884,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03374.cif

Structure  SPKB03374.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2721.28624

Aliphatic index  124.2307692

Isoelectric point  7.251560689

Charge (pH=7)   -0.034426367

Topological polar surface area  977.81

Aromaticity  0.076923077

Average rotatable bonds  3.307692308

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  37

X logP energy  -6.2787

Hydropathy 



Literature Information


Title  A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation.

DOI  10.1016/s0165-5728(98)00204-5,

Publication Year  1998

PubMed ID  9916893,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.