SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03372

Signal sequence   MKSCGLLPFTVLLALGILAPWTVEG

Length  25

Organism  Mus musculus (Mouse)

UniProt ID  P97430,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03372.cif

Structure  SPKB03372.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2630.24214

Aliphatic index  140.4

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  883.94

Aromaticity  0.08

Average rotatable bonds  3.24

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -2.9881

Hydropathy 



Literature Information


Title  The cloning and characterization of a murine secretory leukocyte protease inhibitor cDNA.

DOI  10.1006/bbrc.1997.6358,

Publication Year  1997

PubMed ID  9126337,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.