SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03364

Signal sequence   MNSLVMISLALLVMTGVES

Length  19

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  P86408,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03364.cif

Structure  SPKB03364.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2008.47754

Aliphatic index  153.6842105

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  748.43

Aromaticity  0

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -5.6683

Hydropathy 



Literature Information


Title  Evolutionary diversification of Mesobuthus alpha-scorpion toxins affecting sodium channels.

DOI  10.1074/mcp.M111.012054,

Publication Year  2012

PubMed ID  21969612,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.