SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03361

Signal sequence   MKSKFKLTTAAAMLGLMVLAGGAQA

Length  25

Organism  Alcaligenes faecalis

UniProt ID  P84888,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2H3X,

Predicted Structure ID  SPKB03361.cif

Structure  SPKB03361.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2510.10974

Aliphatic index  98

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  943.56

Aromaticity  0.04

Average rotatable bonds  3.48

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  36

X logP energy  -8.2041

Hydropathy 



Literature Information


Title  Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis. Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans.

DOI  10.1111/j.1742-4658.2005.04990.x,

Publication Year  2005

PubMed ID  16279953,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.