SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03360

Signal sequence   MRWLDKFGESLSRSVAHKTSRRSVLRSVGKLMVGSAFVLPVLPVARA

Length  47

Organism  Alcaligenes faecalis

UniProt ID  P84887,

Motif  1..47



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03360.cif

Structure  SPKB03360.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5197.20074

Aliphatic index  101.4893617

Isoelectric point  12.51641072

Charge (pH=7)   7.090210028

Topological polar surface area  2114.71

Aromaticity  0.063829787

Average rotatable bonds  3.680851064

Number of hydrogen bond donors  79

Number of hydrogen bond acceptors  70

X logP energy  -20.13168

Hydropathy 



Literature Information


Title  Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis. Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans.

DOI  10.1111/j.1742-4658.2005.04990.x,

Publication Year  2005

PubMed ID  16279953,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.