General Information
SPKB ID SPKB03357
Signal sequence MKAFYGMLVIFILCSTCYISVDS
Length 23
Organism Tityus discrepans (Venezuelan scorpion)
UniProt ID P84777,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03357.cif
Physicochemical Information
Molecular weight 2605.17854
Aliphatic index 114.3478261
Isoelectric point 6.060307613
Charge (pH=7) -0.127514511
Topological polar surface area 888.22
Aromaticity 0.173913043
Average rotatable bonds 3.608695652
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 36
X logP energy -4.0331
Hydropathy 
Literature Information
Title Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.
DOI 10.1016/j.abb.2004.07.010,
Publication Year 2004
PubMed ID 15369825,
Patent ID NA,
