SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03353

Signal sequence   MRNDVLTLTNPMEEKELEQILGG

Length  23

Organism  Mediterraneibacter gnavus (Ruminococcus gnavus)

UniProt ID  P83674,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03353.cif

Structure  SPKB03353.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2631.01124

Aliphatic index  97.39130435

Isoelectric point  3.98690266

Charge (pH=7)   -2.994767071

Topological polar surface area  1138.88

Aromaticity  0

Average rotatable bonds  4

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -10.67033

Hydropathy 



Literature Information


Title  Ruminococcin A, a new lantibiotic produced by a Ruminococcus gnavus strain isolated from human feces.

DOI  10.1128/AEM.67.9.4111-4118.2001,

Publication Year  2001

PubMed ID  11526013,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.