SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03346

Signal sequence   MNFSKIFIFVVLAVLLLCSQTEA

Length  23

Organism  Anopheles gambiae (African malaria mosquito)

UniProt ID  P82290,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03346.cif

Structure  SPKB03346.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2587.17384

Aliphatic index  148.2608696

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  913.71

Aromaticity  0.130434783

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -3.7406

Hydropathy 



Literature Information


Title  Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae.

DOI  10.1046/j.1365-2583.2000.00164.x,

Publication Year  2000

PubMed ID  10672074,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.