SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03344

Signal sequence   MSLSVSRRLAAVTAFAVAGLFASAVPAALAAPSAVAA

Length  37

Organism  Streptomyces exfoliatus (Streptomyces hydrogenans)

UniProt ID  P81715,

Motif  1..37



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03344.cif

Structure  SPKB03344.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3487.12124

Aliphatic index  119.1891892

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1338.52

Aromaticity  0.054054054

Average rotatable bonds  2.837837838

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  47

X logP energy  -14.65476

Hydropathy 



Literature Information


Title  Characterization of the leupeptin-inactivating enzyme from Streptomyces exfoliatus SMF13 which produces leupeptin.

DOI  10.1042/bj3310539,

Publication Year  1998

PubMed ID  9531495,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.