SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03329

Signal sequence   MAWTVLLLGLLSHCTGS

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P80748,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03329.cif

Structure  SPKB03329.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.17974

Aliphatic index  137.6470588

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  654.31

Aromaticity  0.058823529

Average rotatable bonds  3.294117647

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -4.5568

Hydropathy 



Literature Information


Title  Amino acid sequence of the lambda type light chain of a human IgGl myeloma protein (MOT) with unusual antigenicity: a possible new subgroup of lambda chain having a unique N-terminal sequence.

DOI  10.1016/0161-5890(80)90010-3,

Publication Year  1980

PubMed ID  6780787,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.