General Information
SPKB ID SPKB03329
Signal sequence MAWTVLLLGLLSHCTGS
Length 17
Organism Homo sapiens (Human)
UniProt ID P80748,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03329.cif
Physicochemical Information
Molecular weight 1802.17974
Aliphatic index 137.6470588
Isoelectric point 7.35902981
Charge (pH=7) 0.026918674
Topological polar surface area 654.31
Aromaticity 0.058823529
Average rotatable bonds 3.294117647
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -4.5568
Hydropathy
Literature Information
Title Amino acid sequence of the lambda type light chain of a human IgGl myeloma protein (MOT) with unusual antigenicity: a possible new subgroup of lambda chain having a unique N-terminal sequence.
DOI 10.1016/0161-5890(80)90010-3,
Publication Year 1980
PubMed ID 6780787,
Patent ID NA,