SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03328

Signal sequence   MPRAPALLFSCLLGLCALVPRLPG

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  P80747,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03328.cif

Structure  SPKB03328.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2509.17064

Aliphatic index  138.3333333

Isoelectric point  8.834915637

Charge (pH=7)   1.874028245

Topological polar surface area  841.49

Aromaticity  0.041666667

Average rotatable bonds  3.083333333

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.75106

Hydropathy 



Literature Information


Title  Bovine PAS-6/7 binds alpha v beta 5 integrins and anionic phospholipids through two domains.

DOI  10.1021/bi963119m,

Publication Year  1997

PubMed ID  9154926,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.